The MEMO1 Antibody from MyBioSource.com is a Mouse Monoclonal antibody to MEMO1. This antibody recognizes Human antigen. The MEMO1 Antibody has been validated for the following applications: EIA, Immunoassay, ELISA, Flow Cytometry, and Western Blot.
Description
MEMO1 (Mediator of ErbB2-driven cell motility 1) is a 297 amino acid protein. It is thought to relax extracellular chemotactic signals that are targeted at the microtubule cytoskeleton, thereby controlling cell migration. Additionally, MEMO1 is required for breast carcinoma migration, suggesting an important role in tumorigenesis. The MEMO1-RHOA-DIAPH1 signaling pathway plays an important role in ERBB2-dependent stabilization of microtubules at the cell cortex. It controls the localization of APC and CLASP2 to the cell membrane, via the regulation of GSK3B activity